GO Annotations Graph

• Symbol: Dsp
• Name: desmoplakin
• ID: MGI:109611

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:227218
Molecular Function	GO:0005515	protein binding	IPI	J:170871
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:164563
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0005198	structural molecule activity	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:93314
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:85619
Cellular Component	GO:0030054	cell junction	IEA	J:72247
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:51903
Cellular Component	GO:0005911	cell-cell junction	IDA	J:51903
Cellular Component	GO:0005911	cell-cell junction	IDA	J:51903
Cellular Component	GO:0005911	cell-cell junction	IDA	J:146976
Cellular Component	GO:0005911	cell-cell junction	IDA	J:51903
Cellular Component	GO:0001533	cornified envelope	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:72247
Cellular Component	GO:0030057	desmosome	IDA	J:93314
Cellular Component	GO:0030057	desmosome	IDA	J:236209
Cellular Component	GO:0030057	desmosome	ISO	J:155856
Cellular Component	GO:0030057	desmosome	IDA	J:105239
Cellular Component	GO:0030057	desmosome	IDA	J:148138
Cellular Component	GO:0030057	desmosome	IDA	J:87593
Cellular Component	GO:0005916	fascia adherens	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	IDA	J:227218
Cellular Component	GO:0014704	intercalated disc	ISO	J:164563
Cellular Component	GO:0014704	intercalated disc	IBA	J:265628
Cellular Component	GO:0014704	intercalated disc	IDA	J:124009
Cellular Component	GO:0005882	intermediate filament	IDA	J:125067
Cellular Component	GO:0005882	intermediate filament	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:156343
Cellular Component	GO:0005886	plasma membrane	IDA	J:227218
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0034332	adherens junction organization	IMP	J:73084
Biological Process	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	ISO	J:164563
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:51903
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:73084
Biological Process	GO:0002934	desmosome organization	IMP	J:125067
Biological Process	GO:0002934	desmosome organization	IMP	J:51903
Biological Process	GO:0090136	epithelial cell-cell adhesion	ISO	J:255307
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	IBA	J:265628
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	IMP	J:51903
Biological Process	GO:0045109	intermediate filament organization	IMP	J:125067
Biological Process	GO:0030216	keratinocyte differentiation	ISO	J:164563
Biological Process	GO:0018149	peptide cross-linking	ISO	J:164563
Biological Process	GO:0150105	protein localization to cell-cell junction	IMP	J:125067
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0098911	regulation of ventricular cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0043588	skin development	IBA	J:265628
Biological Process	GO:0043588	skin development	IMP	J:73084
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	IMP	J:125067
Biological Process	GO:0042060	wound healing	IBA	J:265628