GO Annotations Graph

• Symbol: Nxn
• Name: nucleoredoxin
• ID: MGI:109331

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200438
Molecular Function	GO:0005515	protein binding	IPI	J:169113
Molecular Function	GO:0005515	protein binding	IPI	J:169975
Molecular Function	GO:0005515	protein binding	IPI	J:192848
Molecular Function	GO:0047134	protein-disulfide reductase (NAD(P)) activity	IEA	J:72245
Molecular Function	GO:0004791	thioredoxin-disulfide reductase activity	IBA	J:265628
Molecular Function	GO:0004791	thioredoxin-disulfide reductase activity	IDA	J:38410
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:38410
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0098869	cellular oxidant detoxification	IDA	J:38410
Biological Process	GO:0072359	circulatory system development	IMP	J:167570
Biological Process	GO:0001701	in utero embryonic development	IMP	J:240631
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0031397	negative regulation of protein ubiquitination	IMP	J:167570
Biological Process	GO:0031397	negative regulation of protein ubiquitination	IBA	J:265628
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IMP	J:167570
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0016055	Wnt signaling pathway	ISO	J:164563