GO Annotations Graph

• Symbol: Cbx3
• Name: chromobox 3
• ID: MGI:108515

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:305429
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:1990226	histone methyltransferase binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0035064	methylated histone binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:210023
Molecular Function	GO:0005515	protein binding	IPI	J:113780
Molecular Function	GO:0005515	protein binding	IPI	J:151987
Molecular Function	GO:0005515	protein binding	IPI	J:94471
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:210023
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:111226
Cellular Component	GO:0061793	chromatin lock complex	ISO	J:164563
Cellular Component	GO:0010369	chromocenter	IDA	J:94471
Cellular Component	GO:0000775	chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0000779	condensed chromosome, centromeric region	IDA	J:133037
Cellular Component	GO:0000791	euchromatin	ISO	J:164563
Cellular Component	GO:0000792	heterochromatin	ISO	J:164563
Cellular Component	GO:0000792	heterochromatin	IDA	J:58506
Cellular Component	GO:0005635	nuclear envelope	IDA	J:133017
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573393
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:158807
Cellular Component	GO:0005634	nucleus	IDA	J:164348
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:133036
Cellular Component	GO:0005721	pericentric heterochromatin	IBA	J:265628
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0035985	senescence-associated heterochromatin focus	ISO	J:155856
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Cellular Component	GO:0005819	spindle	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0031507	heterochromatin formation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:58506
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048511	rhythmic process	IEA	J:60000