GO Annotations Graph

• Symbol: Tinf2
• Name: Terf1 (TRF1)-interacting nuclear factor 2
• ID: MGI:107246

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:82975
Molecular Function	GO:0042162	telomeric DNA binding	IDA	J:199000
Molecular Function	GO:0042162	telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0042162	telomeric DNA binding	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:199000
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:82975
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0000783	nuclear telomere cap complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912355
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0010370	perinucleolar chromocenter	ISO	J:164563
Cellular Component	GO:0070187	shelterin complex	ISO	J:164563
Cellular Component	GO:0070187	shelterin complex	IBA	J:265628
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0010836	negative regulation of protein ADP-ribosylation	ISO	J:164563
Biological Process	GO:0032205	negative regulation of telomere maintenance	IDA	J:82975
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0032206	positive regulation of telomere maintenance	NAS	J:319993
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	ISO	J:164563
Biological Process	GO:1904356	regulation of telomere maintenance via telomere lengthening	ISO	J:164563
Biological Process	GO:1904356	regulation of telomere maintenance via telomere lengthening	IBA	J:265628
Biological Process	GO:0032202	telomere assembly	ISO	J:164563
Biological Process	GO:0016233	telomere capping	ISO	J:164563
Biological Process	GO:0016233	telomere capping	IBA	J:265628