GO Annotations Graph

• Symbol: Aurkb
• Name: aurora kinase B
• ID: MGI:107168

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0044022	histone H3S28 kinase activity	IDA	J:203428
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:203428
Molecular Function	GO:0004672	protein kinase activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:272927
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAS	Reactome:R-MMU-9023138
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0010369	chromocenter	IDA	J:147064
Cellular Component	GO:0005694	chromosome	IDA	J:240155
Cellular Component	GO:0032133	chromosome passenger complex	ISO	J:164563
Cellular Component	GO:0032133	chromosome passenger complex	IBA	J:265628
Cellular Component	GO:0032133	chromosome passenger complex	IDA	J:162081
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0000779	condensed chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0000779	condensed chromosome, centromeric region	IDA	J:90544
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0000776	kinetochore	ISO	J:191250
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:164563
Cellular Component	GO:0030496	midbody	ISO	J:155856
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0030496	midbody	IDA	J:46390
Cellular Component	GO:1990023	mitotic spindle midzone	IDA	J:90544
Cellular Component	GO:0097431	mitotic spindle pole	IDA	J:240155
Cellular Component	GO:0097431	mitotic spindle pole	ISO	J:191250
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9023138
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:90544
Cellular Component	GO:0005819	spindle	ISO	J:155856
Cellular Component	GO:0005876	spindle microtubule	IBA	J:265628
Cellular Component	GO:0051233	spindle midzone	IBA	J:265628
Cellular Component	GO:0031616	spindle pole centrosome	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0044839	cell cycle G2/M phase transition	ISO	J:164563
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0036089	cleavage furrow formation	ISO	J:155856
Biological Process	GO:0036089	cleavage furrow formation	ISO	J:164563
Biological Process	GO:0000278	mitotic cell cycle	NAS	J:319980
Biological Process	GO:0000281	mitotic cytokinesis	NAS	J:319980
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	IEA	J:72247
Biological Process	GO:0051256	mitotic spindle midzone assembly	ISO	J:164563
Biological Process	GO:0051256	mitotic spindle midzone assembly	NAS	J:319980
Biological Process	GO:0007052	mitotic spindle organization	NAS	J:319980
Biological Process	GO:0007052	mitotic spindle organization	IBA	J:265628
Biological Process	GO:0002903	negative regulation of B cell apoptotic process	ISO	J:164563
Biological Process	GO:0045824	negative regulation of innate immune response	ISO	J:164563
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	NAS	J:319980
Biological Process	GO:0032467	positive regulation of cytokinesis	ISO	J:164563
Biological Process	GO:1905116	positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	NAS	J:319980
Biological Process	GO:1903490	positive regulation of mitotic cytokinesis	NAS	J:319980
Biological Process	GO:0062033	positive regulation of mitotic sister chromatid segregation	ISO	J:164563
Biological Process	GO:1901970	positive regulation of mitotic sister chromatid separation	NAS	J:319980
Biological Process	GO:0001934	positive regulation of protein phosphorylation	NAS	J:319980
Biological Process	GO:0051973	positive regulation of telomerase activity	ISO	J:164563
Biological Process	GO:1904355	positive regulation of telomere capping	ISO	J:164563
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0043687	post-translational protein modification	IDA	J:203428
Biological Process	GO:0034501	protein localization to kinetochore	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	NAS	J:319980
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0032465	regulation of cytokinesis	IBA	J:265628
Biological Process	GO:0007051	spindle organization	ISO	J:164563