Six4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Six4
sine oculis-related homeobox 4
MGI:106034

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:88186
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:103002
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:88186
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:103002
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:200376
Molecular Function	GO:0005515	protein binding	IPI	J:212814
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:103002
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:35368
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:51236
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:51236
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:52918
Cellular Component	GO:0005634	nucleus	IDA	J:52918
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:51236
Cellular Component	GO:0005634	nucleus	IDA	J:35368
Cellular Component	GO:0005634	nucleus	IC	J:88186
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Biological Process	GO:0048856	anatomical structure development	IGI	J:108725
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	IGI	J:163483
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:98519
Biological Process	GO:0061197	fungiform papilla morphogenesis	IMP	J:190431
Biological Process	GO:0048699	generation of neurons	IMP	J:114468
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:98519
Biological Process	GO:0008584	male gonad development	IMP	J:204550
Biological Process	GO:0030238	male sex determination	IMP	J:204550
Biological Process	GO:0046661	male sex differentiation	IMP	J:204550
Biological Process	GO:0072075	metanephric mesenchyme development	IMP	J:172983
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0051451	myoblast migration	IGI	J:98519
Biological Process	GO:0051451	myoblast migration	IGI	J:98519
Biological Process	GO:0061055	myotome development	IMP	J:156719
Biological Process	GO:0061055	myotome development	IMP	J:98519
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:98519
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:103002
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:165033
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:114468
Biological Process	GO:1902725	negative regulation of satellite cell differentiation	IMP	J:165033
Biological Process	GO:0030910	olfactory placode formation	IMP	J:145187
Biological Process	GO:0060037	pharyngeal system development	IMP	J:108725
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IMP	J:172983
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:103002
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:172983
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:156719
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:122815
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:204550
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:88186
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:103002
Biological Process	GO:0072107	positive regulation of ureteric bud formation	IMP	J:172983
Biological Process	GO:0034504	protein localization to nucleus	IDA	J:113793
Biological Process	GO:0072095	regulation of branch elongation involved in ureteric bud branching	IMP	J:172983
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0050678	regulation of epithelial cell proliferation	IMP	J:145187
Biological Process	GO:0010468	regulation of gene expression	IGI	J:178379
Biological Process	GO:0032880	regulation of protein localization	IGI	J:178379
Biological Process	GO:0008582	regulation of synaptic assembly at neuromuscular junction	IGI	J:178379
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045214	sarcomere organization	IMP	J:178379
Biological Process	GO:0098528	skeletal muscle fiber differentiation	IMP	J:178379
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:122815
Biological Process	GO:0007519	skeletal muscle tissue development	IGI	J:98519
Biological Process	GO:0048538	thymus development	IGI	J:108725
Biological Process	GO:0043586	tongue development	IMP	J:190431
Biological Process	GO:0061551	trigeminal ganglion development	IMP	J:114468

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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