Sox18 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Sox18
SRY (sex determining region Y)-box 18
MGI:103559

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:81702
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:81702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:88479
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:28005
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:61488
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:175110
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:28005
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:88479
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:143564
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:175110
Cellular Component	GO:0005634	nucleus	IC	J:81702
Cellular Component	GO:0005634	nucleus	IDA	J:143564
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:197716
Biological Process	GO:0001525	angiogenesis	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IGI	J:113127
Biological Process	GO:0001568	blood vessel development	IMP	J:61488
Biological Process	GO:0001568	blood vessel development	IMP	J:150211
Biological Process	GO:0048469	cell maturation	IDA	J:160232
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:123026
Biological Process	GO:0060956	endocardial cell differentiation	IGI	J:123026
Biological Process	GO:0060214	endocardium formation	IGI	J:123026
Biological Process	GO:0061028	establishment of endothelial barrier	ISO	J:164563
Biological Process	GO:0022405	hair cycle process	ISO	J:164563
Biological Process	GO:0001942	hair follicle development	IMP	J:66010
Biological Process	GO:0001942	hair follicle development	IMP	J:61488
Biological Process	GO:0007507	heart development	IMP	J:61488
Biological Process	GO:0001701	in utero embryonic development	IMP	J:143564
Biological Process	GO:0001701	in utero embryonic development	IMP	J:150211
Biological Process	GO:0001701	in utero embryonic development	IMP	J:61488
Biological Process	GO:0001945	lymph vessel development	IMP	J:150354
Biological Process	GO:0001945	lymph vessel development	IMP	J:6220
Biological Process	GO:0001946	lymphangiogenesis	ISO	J:164563
Biological Process	GO:0001946	lymphangiogenesis	IBA	J:265628
Biological Process	GO:0001946	lymphangiogenesis	IMP	J:143564
Biological Process	GO:0060836	lymphatic endothelial cell differentiation	IMP	J:143564
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:143564
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:175110
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:61488
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:143564
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:67559
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:88479
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:28005
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:81702
Biological Process	GO:0072091	regulation of stem cell proliferation	IDA	J:160232
Biological Process	GO:0048866	stem cell fate specification	IDA	J:160232
Biological Process	GO:0001944	vasculature development	IMP	J:150211
Biological Process	GO:0001570	vasculogenesis	IBA	J:265628
Biological Process	GO:0001570	vasculogenesis	IGI	J:113127

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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