GO Annotations Graph

• Symbol: Mcf2l
• Name: mcf.2 transforming sequence-like
• ID: MGI:103263

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	IDA	J:83589
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:155856
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IDA	J:83589
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:114759
Molecular Function	GO:0005515	protein binding	IPI	J:245248
Molecular Function	GO:0005515	protein binding	IPI	J:118143
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0012505	endomembrane system	ISO	J:164563
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0019898	extrinsic component of membrane	ISO	J:155856
Cellular Component	GO:0019898	extrinsic component of membrane	IBA	J:265628
Cellular Component	GO:0030027	lamellipodium	IDA	J:83589
Cellular Component	GO:0016020	membrane	IDA	J:83589
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	ISO	J:155856
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:118143
Biological Process	GO:0007266	Rho protein signal transduction	IDA	J:83589