Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables 1-phosphatidylinositol binding activity and guanyl-nucleotide exchange factor activity. Acts upstream of or within Rho protein signal transduction; positive regulation of transcription by RNA polymerase II; and regulation of catalytic activity. Located in lamellipodium and membrane. Is expressed in nervous system and retina. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like).