GO Annotations Graph

• Symbol: Ube2b
• Name: ubiquitin-conjugating enzyme E2B
• ID: MGI:102944

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:81138
Molecular Function	GO:0005515	protein binding	IPI	J:123383
Molecular Function	GO:0005515	protein binding	IPI	J:123383
Molecular Function	GO:0005515	protein binding	IPI	J:86438
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IBA	J:265628
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IGI	J:86438
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IGI	J:123383
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IDA	J:86438
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IDA	J:123383
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:92954
Cellular Component	GO:0000785	chromatin	IDA	J:95995
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0033503	HULC complex	ISO	J:164563
Cellular Component	GO:0033503	HULC complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0005657	replication fork	ISO	J:164563
Cellular Component	GO:0001741	XY body	IDA	J:92954
Biological Process	GO:0006915	apoptotic process	IMP	J:81811
Biological Process	GO:0006915	apoptotic process	IMP	J:81811
Biological Process	GO:0051026	chiasma assembly	IMP	J:81811
Biological Process	GO:0006325	chromatin organization	IMP	J:124051
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IBA	J:265628
Biological Process	GO:0035234	ectopic germ cell programmed cell death	IMP	J:81811
Biological Process	GO:0033522	histone H2A ubiquitination	ISO	J:164563
Biological Process	GO:0016574	histone ubiquitination	IBA	J:265628
Biological Process	GO:0001701	in utero embryonic development	IGI	J:91848
Biological Process	GO:0000237	leptotene	IMP	J:147391
Biological Process	GO:0045141	meiotic telomere clustering	IMP	J:147391
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:81811
Biological Process	GO:0043951	negative regulation of cAMP-mediated signaling	ISO	J:164563
Biological Process	GO:0051093	negative regulation of developmental process	IMP	J:81811
Biological Process	GO:1901874	negative regulation of post-translational protein modification	IMP	J:124051
Biological Process	GO:2000242	negative regulation of reproductive process	IMP	J:81811
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:150916
Biological Process	GO:0010845	positive regulation of reciprocal meiotic recombination	IMP	J:81811
Biological Process	GO:0006301	postreplication repair	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0051865	protein autoubiquitination	ISO	J:164563
Biological Process	GO:0070979	protein K11-linked ubiquitination	ISO	J:164563
Biological Process	GO:0070936	protein K48-linked ubiquitination	ISO	J:164563
Biological Process	GO:0070534	protein K63-linked ubiquitination	ISO	J:164563
Biological Process	GO:0006513	protein monoubiquitination	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	IBA	J:265628
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0009411	response to UV	ISO	J:164563
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0007288	sperm axoneme assembly	IMP	J:84560
Biological Process	GO:0007283	spermatogenesis	TAS	J:52347
Biological Process	GO:0070193	synaptonemal complex organization	IMP	J:124051
Biological Process	GO:0070193	synaptonemal complex organization	IMP	J:81811
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563