GO Annotations Graph

• Symbol: Acsl1
• Name: acyl-CoA synthetase long-chain family member 1
• ID: MGI:102797

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043758	acetate-CoA ligase (ADP-forming) activity	IEA	J:72245
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	ISO	J:155856
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ISO	J:155856
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0090434	oleoyl-CoA ligase activity	ISO	J:155856
Molecular Function	GO:0050197	phytanate-CoA ligase activity	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0033211	adiponectin-activated signaling pathway	IMP	J:166293
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0015908	fatty acid transport	ISO	J:155856
Biological Process	GO:0015908	fatty acid transport	ISO	J:164563
Biological Process	GO:0008610	lipid biosynthetic process	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0044539	long-chain fatty acid import into cell	ISO	J:164563
Biological Process	GO:0044539	long-chain fatty acid import into cell	ISO	J:155856
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0001676	long-chain fatty acid metabolic process	IBA	J:265628
Biological Process	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	ISO	J:155856
Biological Process	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	IBA	J:265628
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:162996
Biological Process	GO:0010747	positive regulation of long-chain fatty acid import across plasma membrane	ISO	J:155856
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	IMP	J:166293
Biological Process	GO:0010033	response to organic substance	ISO	J:155856
Biological Process	GO:0019432	triglyceride biosynthetic process	ISO	J:155856
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	IBA	J:265628
Biological Process	GO:0042178	xenobiotic catabolic process	ISO	J:155856