About   Help   FAQ
GO Annotations Graph
Symbol
Name
ID
Cav1
caveolin 1, caveolae protein
MGI:102709

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0051117ATPase bindingISOJ:164563
Molecular FunctionGO:0019899enzyme bindingISOJ:164563
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0042802identical protein bindingIPIJ:30626
Molecular FunctionGO:0070320inward rectifier potassium channel inhibitor activityISOJ:164563
Molecular FunctionGO:0019900kinase bindingISOJ:155856
Molecular FunctionGO:0060090molecular adaptor activityIDAJ:215922
Molecular FunctionGO:0060090molecular adaptor activityIBAJ:265628
Molecular FunctionGO:0050998nitric-oxide synthase bindingISOJ:155856
Molecular FunctionGO:0050998nitric-oxide synthase bindingISOJ:164563
Molecular FunctionGO:0050998nitric-oxide synthase bindingIPIJ:215922
Molecular FunctionGO:0016504peptidase activator activityIMPJ:120811
Molecular FunctionGO:0005515protein bindingIPIJ:277932
Molecular FunctionGO:0005515protein bindingIPIJ:113994
Molecular FunctionGO:0005515protein bindingIPIJ:180559
Molecular FunctionGO:0005515protein bindingIPIJ:187544
Molecular FunctionGO:0005515protein bindingIPIJ:269642
Molecular FunctionGO:0005515protein bindingIPIJ:159068
Molecular FunctionGO:0005515protein bindingIPIJ:282620
Molecular FunctionGO:0005515protein bindingIPIJ:116930
Molecular FunctionGO:0005515protein bindingIPIJ:230032
Molecular FunctionGO:0005515protein bindingIPIJ:126756
Molecular FunctionGO:0005515protein bindingIPIJ:122666
Molecular FunctionGO:0005515protein bindingIPIJ:78798
Molecular FunctionGO:0005515protein bindingIPIJ:182176
Molecular FunctionGO:0005515protein bindingIPIJ:104986
Molecular FunctionGO:0005515protein bindingIPIJ:122666
Molecular FunctionGO:0005515protein bindingIPIJ:176254
Molecular FunctionGO:0046982protein heterodimerization activityIPIJ:217293
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0019901protein kinase bindingIPIJ:215922
Molecular FunctionGO:0019901protein kinase bindingIBAJ:265628
Molecular FunctionGO:0044877protein-containing complex bindingISOJ:164563
Molecular FunctionGO:0030674protein-macromolecule adaptor activityIDAJ:215922
Molecular FunctionGO:0033612receptor serine/threonine kinase bindingISOJ:155856
Molecular FunctionGO:0005102signaling receptor bindingISOJ:164563
Molecular FunctionGO:0031267small GTPase bindingISOJ:164563
Molecular FunctionGO:0000149SNARE bindingISOJ:155856
Molecular FunctionGO:0019905syntaxin bindingISOJ:155856
Molecular FunctionGO:0044325transmembrane transporter bindingISOJ:164563
Molecular FunctionGO:0044325transmembrane transporter bindingISOJ:155856
Molecular FunctionGO:0044325transmembrane transporter bindingIBAJ:265628
Cellular ComponentGO:0002080acrosomal membraneIDAJ:73676
Cellular ComponentGO:0016324apical plasma membraneISOJ:164563
Cellular ComponentGO:0009925basal plasma membraneISOJ:155856
Cellular ComponentGO:0016323basolateral plasma membraneISOJ:164563
Cellular ComponentGO:0005901caveolaIDAJ:30626
Cellular ComponentGO:0005901caveolaISOJ:155856
Cellular ComponentGO:0005901caveolaIDAJ:75490
Cellular ComponentGO:0005901caveolaIDAJ:120010
Cellular ComponentGO:0005901caveolaIDAJ:75490
Cellular ComponentGO:0005901caveolaISOJ:201740
Cellular ComponentGO:0005901caveolaISOJ:73065
Cellular ComponentGO:0005901caveolaIDAJ:40432
Cellular ComponentGO:0005901caveolaIDAJ:37694
Cellular ComponentGO:0005901caveolaIDAJ:130715
Cellular ComponentGO:0005901caveolaIDAJ:129658
Cellular ComponentGO:0005901caveolaISOJ:73065
Cellular ComponentGO:0005901caveolaTASJ:55894
Cellular ComponentGO:0002095caveolar macromolecular signaling complexIDAJ:75490
Cellular ComponentGO:0005938cell cortexIDAJ:59358
Cellular ComponentGO:0009986cell surfaceISOJ:155856
Cellular ComponentGO:0005929ciliumIDAJ:73676
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0031410cytoplasmic vesicleISOJ:155856
Cellular ComponentGO:0031410cytoplasmic vesicleISOJ:164563
Cellular ComponentGO:0031410cytoplasmic vesicleIBAJ:265628
Cellular ComponentGO:0031410cytoplasmic vesicleISOJ:189648
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005783endoplasmic reticulumISOJ:164563
Cellular ComponentGO:0005783endoplasmic reticulumIDAJ:120537
Cellular ComponentGO:0005768endosomeISOJ:164563
Cellular ComponentGO:0005925focal adhesionISOJ:164563
Cellular ComponentGO:0005925focal adhesionISOJ:155856
Cellular ComponentGO:0005925focal adhesionIDAJ:217289
Cellular ComponentGO:0005925focal adhesionIBAJ:265628
Cellular ComponentGO:0005794Golgi apparatusISOJ:155856
Cellular ComponentGO:0005794Golgi apparatusIBAJ:265628
Cellular ComponentGO:0005794Golgi apparatusIDAJ:120537
Cellular ComponentGO:0000139Golgi membraneISOJ:164563
Cellular ComponentGO:0005811lipid dropletISOJ:155856
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0016020membraneIDAJ:52977
Cellular ComponentGO:0016020membraneIDAJ:167702
Cellular ComponentGO:0016020membraneIDAJ:73676
Cellular ComponentGO:0016020membraneIDAJ:116472
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0045121membrane raftISOJ:164563
Cellular ComponentGO:0045121membrane raftIDAJ:79453
Cellular ComponentGO:0045121membrane raftIDAJ:85358
Cellular ComponentGO:0045121membrane raftIDAJ:73676
Cellular ComponentGO:0045121membrane raftIDAJ:120010
Cellular ComponentGO:0045121membrane raftIDAJ:122666
Cellular ComponentGO:0045121membrane raftIDAJ:54097
Cellular ComponentGO:0045121membrane raftIDAJ:120537
Cellular ComponentGO:0045121membrane raftIDAJ:79783
Cellular ComponentGO:0045121membrane raftIDAJ:120010
Cellular ComponentGO:0005739mitochondrionISOJ:155856
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:155856
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:164563
Cellular ComponentGO:0048471perinuclear region of cytoplasmIBAJ:265628
Cellular ComponentGO:0048471perinuclear region of cytoplasmIDAJ:30626
Cellular ComponentGO:0005778peroxisomal membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneIDAJ:91698
Cellular ComponentGO:0005886plasma membraneIDAJ:30626
Cellular ComponentGO:0005886plasma membraneIDAJ:79453
Cellular ComponentGO:0005886plasma membraneIDAJ:116899
Cellular ComponentGO:0005886plasma membraneIDAJ:75490
Cellular ComponentGO:0005886plasma membraneIDAJ:79453
Cellular ComponentGO:0005886plasma membraneIDAJ:120537
Cellular ComponentGO:0005886plasma membraneIDAJ:120811
Cellular ComponentGO:0005886plasma membraneIDAJ:86955
Cellular ComponentGO:0005886plasma membraneIDAJ:186896
Cellular ComponentGO:0005886plasma membraneIDAJ:116292
Cellular ComponentGO:0005886plasma membraneIDAJ:116292
Cellular ComponentGO:0032991protein-containing complexISOJ:155856
Cellular ComponentGO:0032991protein-containing complexISOJ:164563
Cellular ComponentGO:0032991protein-containing complexIDAJ:215922
Cellular ComponentGO:0032991protein-containing complexIPIJ:122666
Cellular ComponentGO:0032991protein-containing complexIPIJ:122666
Cellular ComponentGO:0032991protein-containing complexIPIJ:122666
Cellular ComponentGO:0032991protein-containing complexISOJ:201740
Cellular ComponentGO:0042383sarcolemmaIBAJ:265628
Biological ProcessGO:0001525angiogenesisIGIJ:109484
Biological ProcessGO:0086098angiotensin-activated signaling pathway involved in heart processIGIJ:215922
Biological ProcessGO:0097190apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0071711basement membrane organizationIMPJ:75490
Biological ProcessGO:0055074calcium ion homeostasisIMPJ:82490
Biological ProcessGO:0006816calcium ion transportIMPJ:122666
Biological ProcessGO:0070836caveola assemblyIGIJ:215923
Biological ProcessGO:0070836caveola assemblyISOJ:164563
Biological ProcessGO:0070836caveola assemblyIBAJ:265628
Biological ProcessGO:0070836caveola assemblyIMPJ:109484
Biological ProcessGO:0070836caveola assemblyIDAJ:75490
Biological ProcessGO:0072584caveolin-mediated endocytosisISOJ:164563
Biological ProcessGO:0072584caveolin-mediated endocytosisIMPJ:126756
Biological ProcessGO:0030154cell differentiationIBAJ:265628
Biological ProcessGO:0008283cell population proliferationIMPJ:119709
Biological ProcessGO:0008283cell population proliferationIMPJ:119709
Biological ProcessGO:0008283cell population proliferationIMPJ:82042
Biological ProcessGO:0071360cellular response to exogenous dsRNAISOJ:164563
Biological ProcessGO:0071455cellular response to hyperoxiaISOJ:164563
Biological ProcessGO:0071260cellular response to mechanical stimulusISOJ:155856
Biological ProcessGO:0071375cellular response to peptide hormone stimulusIGIJ:215922
Biological ProcessGO:0071560cellular response to transforming growth factor beta stimulusIMPJ:176254
Biological ProcessGO:0090398cellular senescenceISOJ:155856
Biological ProcessGO:0033344cholesterol effluxISOJ:155856
Biological ProcessGO:0042632cholesterol homeostasisIMPJ:116292
Biological ProcessGO:0019221cytokine-mediated signaling pathwayIMPJ:120010
Biological ProcessGO:0019221cytokine-mediated signaling pathwayIMPJ:120010
Biological ProcessGO:0006897endocytosisTASJ:55894
Biological ProcessGO:0001935endothelial cell proliferationIMPJ:75490
Biological ProcessGO:0051649establishment of localization in cellIMPJ:122666
Biological ProcessGO:0048144fibroblast proliferationIMPJ:82042
Biological ProcessGO:0002067glandular epithelial cell differentiationIMPJ:120010
Biological ProcessGO:0038016insulin receptor internalizationIMPJ:281214
Biological ProcessGO:0006874intracellular calcium ion homeostasisISOJ:155856
Biological ProcessGO:0006874intracellular calcium ion homeostasisIMPJ:120603
Biological ProcessGO:0033484intracellular nitric oxide homeostasisIMPJ:78603
Biological ProcessGO:0007595lactationIMPJ:120010
Biological ProcessGO:0019915lipid storageIMPJ:75490
Biological ProcessGO:0019915lipid storageIMPJ:75490
Biological ProcessGO:0032507maintenance of protein location in cellISOJ:155856
Biological ProcessGO:0030879mammary gland developmentIMPJ:120010
Biological ProcessGO:0030879mammary gland developmentIMPJ:120010
Biological ProcessGO:0030879mammary gland developmentIMPJ:120010
Biological ProcessGO:0060056mammary gland involutionIMPJ:120010
Biological ProcessGO:0000165MAPK cascadeIMPJ:120010
Biological ProcessGO:0051899membrane depolarizationIMPJ:120603
Biological ProcessGO:0046785microtubule polymerizationISOJ:155856
Biological ProcessGO:0046716muscle cell cellular homeostasisIMPJ:120603
Biological ProcessGO:2000811negative regulation of anoikisIMPJ:187544
Biological ProcessGO:2000811negative regulation of anoikisISOJ:164563
Biological ProcessGO:0030514negative regulation of BMP signaling pathwayISOJ:164563
Biological ProcessGO:1905949negative regulation of calcium ion import across plasma membraneISOJ:155856
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayIDAJ:163148
Biological ProcessGO:2001258negative regulation of cation channel activityISOJ:155856
Biological ProcessGO:0008285negative regulation of cell population proliferationIMPJ:119709
Biological ProcessGO:0001960negative regulation of cytokine-mediated signaling pathwayIMPJ:120010
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationISOJ:155856
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationIBAJ:265628
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationIMPJ:75490
Biological ProcessGO:0030857negative regulation of epithelial cell differentiationIMPJ:120010
Biological ProcessGO:0030857negative regulation of epithelial cell differentiationIMPJ:120010
Biological ProcessGO:0070373negative regulation of ERK1 and ERK2 cascadeISOJ:155856
Biological ProcessGO:0048147negative regulation of fibroblast proliferationIMPJ:82042
Biological ProcessGO:1903609negative regulation of inward rectifier potassium channel activityISOJ:164563
Biological ProcessGO:0043407negative regulation of MAP kinase activityIMPJ:120010
Biological ProcessGO:0043409negative regulation of MAPK cascadeIMPJ:120010
Biological ProcessGO:0043409negative regulation of MAPK cascadeIMPJ:82042
Biological ProcessGO:0010656negative regulation of muscle cell apoptotic processISOJ:155856
Biological ProcessGO:0060546negative regulation of necroptotic processIMPJ:192110
Biological ProcessGO:0045665negative regulation of neuron differentiationISOJ:155856
Biological ProcessGO:0045019negative regulation of nitric oxide biosynthetic processIMPJ:82042
Biological ProcessGO:0051001negative regulation of nitric-oxide synthase activityIMPJ:104734
Biological ProcessGO:0051001negative regulation of nitric-oxide synthase activityIMPJ:144878
Biological ProcessGO:0033137negative regulation of peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:1900085negative regulation of peptidyl-tyrosine autophosphorylationIMPJ:215922
Biological ProcessGO:1900085negative regulation of peptidyl-tyrosine autophosphorylationISOJ:164563
Biological ProcessGO:0048550negative regulation of pinocytosisISOJ:164563
Biological ProcessGO:1901380negative regulation of potassium ion transmembrane transportISOJ:164563
Biological ProcessGO:0032091negative regulation of protein bindingISOJ:164563
Biological ProcessGO:0061099negative regulation of protein tyrosine kinase activityISOJ:164563
Biological ProcessGO:0061099negative regulation of protein tyrosine kinase activityIMPJ:215922
Biological ProcessGO:0061099negative regulation of protein tyrosine kinase activityIBAJ:265628
Biological ProcessGO:0031397negative regulation of protein ubiquitinationISOJ:164563
Biological ProcessGO:0031397negative regulation of protein ubiquitinationIMPJ:187544
Biological ProcessGO:0046426negative regulation of receptor signaling pathway via JAK-STATIDAJ:120010
Biological ProcessGO:0046426negative regulation of receptor signaling pathway via JAK-STATIGIJ:120010
Biological ProcessGO:0046426negative regulation of receptor signaling pathway via JAK-STATIMPJ:120010
Biological ProcessGO:0009968negative regulation of signal transductionIDAJ:52621
Biological ProcessGO:0014912negative regulation of smooth muscle cell migrationISOJ:155856
Biological ProcessGO:0048662negative regulation of smooth muscle cell proliferationISOJ:155856
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIIDAJ:163148
Biological ProcessGO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayISOJ:164563
Biological ProcessGO:0042532negative regulation of tyrosine phosphorylation of STAT proteinIMPJ:120010
Biological ProcessGO:0042532negative regulation of tyrosine phosphorylation of STAT proteinIDAJ:120010
Biological ProcessGO:1904706negative regulation of vascular associated smooth muscle cell proliferationISOJ:155856
Biological ProcessGO:0006809nitric oxide biosynthetic processIMPJ:82042
Biological ProcessGO:0010524positive regulation of calcium ion transport into cytosolIDAJ:146324
Biological ProcessGO:0090263positive regulation of canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0043085positive regulation of catalytic activityIMPJ:120811
Biological ProcessGO:0060355positive regulation of cell adhesion molecule productionISOJ:164563
Biological ProcessGO:0030335positive regulation of cell migrationISOJ:164563
Biological ProcessGO:0010875positive regulation of cholesterol effluxISOJ:164563
Biological ProcessGO:0120162positive regulation of cold-induced thermogenesisIMPJ:105133
Biological ProcessGO:0045807positive regulation of endocytosisISOJ:155856
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:155856
Biological ProcessGO:1903071positive regulation of ER-associated ubiquitin-dependent protein catabolic processISOJ:164563
Biological ProcessGO:2001238positive regulation of extrinsic apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:1903598positive regulation of gap junction assemblyIMPJ:215922
Biological ProcessGO:0010628positive regulation of gene expressionIMPJ:215922
Biological ProcessGO:2001244positive regulation of intrinsic apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0031116positive regulation of microtubule polymerizationISOJ:155856
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityISOJ:164563
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:0032092positive regulation of protein bindingISOJ:164563
Biological ProcessGO:0031398positive regulation of protein ubiquitinationISOJ:164563
Biological ProcessGO:0009967positive regulation of signal transductionISOJ:155856
Biological ProcessGO:0034141positive regulation of toll-like receptor 3 signaling pathwayISOJ:164563
Biological ProcessGO:0045907positive regulation of vasoconstrictionISOJ:155856
Biological ProcessGO:0045907positive regulation of vasoconstrictionIMPJ:75490
Biological ProcessGO:0010608post-transcriptional regulation of gene expressionIMPJ:215922
Biological ProcessGO:0008104protein localizationIMPJ:122666
Biological ProcessGO:0015031protein transportIMPJ:126756
Biological ProcessGO:0031623receptor internalizationISOJ:164563
Biological ProcessGO:2000286receptor internalization involved in canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0019065receptor-mediated endocytosis of virus by host cellISOJ:164563
Biological ProcessGO:0030193regulation of blood coagulationISOJ:164563
Biological ProcessGO:1901844regulation of cell communication by electrical coupling involved in cardiac conductionIMPJ:215922
Biological ProcessGO:0051480regulation of cytosolic calcium ion concentrationISOJ:164563
Biological ProcessGO:0051480regulation of cytosolic calcium ion concentrationIBAJ:265628
Biological ProcessGO:2000535regulation of entry of bacterium into host cellISOJ:164563
Biological ProcessGO:0019217regulation of fatty acid metabolic processIMPJ:75490
Biological ProcessGO:0086091regulation of heart rate by cardiac conductionIMPJ:215922
Biological ProcessGO:0098903regulation of membrane repolarization during action potentialISOJ:164563
Biological ProcessGO:0052547regulation of peptidase activityIMPJ:120811
Biological ProcessGO:1900027regulation of ruffle assemblyISOJ:164563
Biological ProcessGO:0006940regulation of smooth muscle contractionIMPJ:120603
Biological ProcessGO:0006940regulation of smooth muscle contractionIMPJ:116899
Biological ProcessGO:0002026regulation of the force of heart contractionIMPJ:104734
Biological ProcessGO:0003057regulation of the force of heart contraction by chemical signalIGIJ:144878
Biological ProcessGO:0098911regulation of ventricular cardiac muscle cell action potentialIMPJ:215922
Biological ProcessGO:0009617response to bacteriumISOJ:164563
Biological ProcessGO:0051592response to calcium ionIDAJ:146324
Biological ProcessGO:0043627response to estrogenISOJ:120010
Biological ProcessGO:0043627response to estrogenIDAJ:120010
Biological ProcessGO:0001666response to hypoxiaIMPJ:122233
Biological ProcessGO:0002931response to ischemiaIMPJ:133702
Biological ProcessGO:0009612response to mechanical stimulusISOJ:155856
Biological ProcessGO:0032570response to progesteroneISOJ:120010
Biological ProcessGO:0007519skeletal muscle tissue developmentIMPJ:117199
Biological ProcessGO:0031295T cell costimulationISOJ:164563
Biological ProcessGO:0006641triglyceride metabolic processIMPJ:75490
Biological ProcessGO:0007260tyrosine phosphorylation of STAT proteinIMPJ:120010
Biological ProcessGO:0001570vasculogenesisIMPJ:122233
Biological ProcessGO:0042310vasoconstrictionIMPJ:120603
Biological ProcessGO:0042060wound healingISOJ:155856

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory