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Ccd Gene Detail
Summary
  • Symbol
    Ccd
  • Name
    cleidocranial dysplasia
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88291
    NCBI Gene: 109920
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 17, Syntenic
  • Mapping Data
    1 experiment
Human Diseases
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  • Diseases
    1 with Ccd mouse models

Human Disease Mouse Models
      
IDs
View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 1 allele in 2 genetic backgrounds
    24 phenotypes from multigenic genotypes
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in embryonic lethality. Heterozygotes show homology to cleidocranial dysplasia, a skeletal disorder in man. It causes partial or complete failure of ossification of clavicles, symphysis pubis, and cranial fontanelles.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-1795
References
more
  • Summaries
    All 7
    Diseases 2
    Phenotypes 6
  • Earliest
    J:64450 Selby PB, et al., Gamma-ray-induced dominant mutations that cause skeletal abnormalities in mice. I. Plan, summary of results and discussion. Mutat Res. 1977 Jun;43(3):357-75
  • Latest
    J:42584 Huang LF, et al., Mouse clavicular development: analysis of wild-type and cleidocranial dysplasia mutant mice. Dev Dyn. 1997 Sep;210(1):33-40

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory