Rr695591 Other Genome Feature Detail

Summary

• Symbol
  Rr695591
• Name
  regulatory region 695591
• Synonyms
  Irf8 +56

• Feature Type
  enhancer
• IDs
  MGI:8246886
• Regulates expression of
  Irf8 (1 regulated gene)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• chr8:121511296-121521637 (GRCm39)

• Genetic Map
  Chromosome 8, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:305266 Murakami K, et al., A RUNX-CBFbeta-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes. Nat Immunol. 2021 Mar;22(3):301-311
• Latest
  J:372258 Yamasaki T, et al., Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation. Cell Rep. 2024 Apr 23;43(4):114107

Rr695591 regulates expression of:

Feature	Feature Type	Location	Reference
Irf8, interferon regulatory factor 8	protein coding gene	Chr8:121463097-121483433 (+)	J:305266