Tg(Rr443-Pkd2*D509V,-lacZ)3Hmd
Transgene Detail

Summary

• Symbol: Tg(Rr443-Pkd2*D509V,-lacZ)3Hmd
• Name: transgene insertion 3, Hiroshi Hamada
• MGI ID: MGI:7514581
• Synonyms: Tg(NDE-hsp-Pkd2*D509V,lacZ)3Hmd
• Transgene: Tg(Rr443-Pkd2*D509V,-lacZ)3Hmd Location: unknown
• Alliance: Tg(Rr443-Pkd2*D509V,-lacZ)3Hmd page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Rr443-Pkd2*D509V,-lacZ)3Hmd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pkd2 (MGI:1099818)	mutation D509V

• Tg(Rr443-Pkd2*D509V,-lacZ)3Hmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nodal (MGI:97359)

• Mutation details: This transgenic mouse strain expresses the Asp509Val variant Pkd2 and lacZ on both node under the control of the mouse node-specific enhancer. (J:187958)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:187958 Yoshiba S, et al., Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2. Science. 2012 Oct 12;338(6104):226-31
• All: 1 reference(s)