Tg(Rr436-GCaMP6)29AHmd
Transgene Detail

Summary

• Symbol: Tg(Rr436-GCaMP6)29AHmd
• Name: transgene insertion 29A, Hiroshi Hamada
• MGI ID: MGI:7492218
• Synonyms: Tg(Nodal NDE-GCaMP6)29AHmd
• Transgene: Tg(Rr436-GCaMP6)29AHmd Location: unknown
• Alliance: Tg(Rr436-GCaMP6)29AHmd page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Tg(Rr436-GCaMP6)29AHmd expression driven by 2 genes
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nodal (MGI:97359)
  mouse	Rr436 (MGI:7492210)

• Mutation details: The transgene contains the a crown cell-specific enhancer derived from the mouse Nodal gene driving expression of the GCaMP6 reporter gene (RSET tag, chicken smooth muscle M13, Jellyfish circularly permutated EGFP (cpEGFP) cDNA, and rat calmodulin (CaM) cDNA (aa.2-148)). Line 29A was generated. (J:336740)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:336740 Katoh TA, et al., Immotile cilia mechanically sense the direction of fluid flow for left-right determination. Science. 2023 Jan 6;379(6627):66-71
• All: 1 reference(s)