Rr174 Other Genome Feature Detail

Summary

• Symbol
  Rr174
• Name
  regulatory region 174
• Synonyms
  Irf8 -50

• Feature Type
  enhancer
• IDs
  MGI:6863879
• Regulates expression of
  Irf8 (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr8:121412733-121413283 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:279982 Fig.S5b coordinates Chr8:120685994-120686544 (GRCm38) = chr8:121412733-121413283 (GRCm39).

• Genetic Map
  Chromosome 8, Syntenic

Strain
Comparison

• SNPs within 2kb
  131 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:279982 Durai V, et al., Cryptic activation of an Irf8 enhancer governs cDC1 fate specification. Nat Immunol. 2019 Sep;20(9):1161-1173

Rr174 regulates expression of:

Feature	Feature Type	Location	Reference
Irf8, interferon regulatory factor 8	protein coding gene	Chr8:121463097-121483433 (+)	J:279982