About   Help   FAQ
Rr172 Other Genome Feature Detail
Summary
  • Symbol
    Rr172
  • Name
    regulatory region 172
  • Synonyms
    AICE, Irf8 +32
  • Feature Type
    enhancer
  • IDs
    MGI:6863877
  • Regulates expression of
    Irf8 (1 regulated gene)
Location &
Maps
more
  • Sequence Map
    Chr8:121495079-121495626 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • J:279982 Fig.S1e coordinates Chr8:120768340-120768887 (GRCm38 according to alignment of sequence: left edge:GTGTTCCTGGGCTGTGGTCATTCCTATTGTATTTGTCTATA; right edge: CTGGTTTCAGGATCGCACCTCACCTACTGGGTGAG): chr8:121495079-121495626 (GRCm39).
  • Genetic Map
    Chromosome 8, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    122 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from multigenic genotypes
    13 phenotype references
References
more
  • Summaries
    All 15
    Phenotypes 13
  • Earliest
    J:279982 Durai V, et al., Cryptic activation of an Irf8 enhancer governs cDC1 fate specification. Nat Immunol. 2019 Sep;20(9):1161-1173
  • Latest
    J:363930 Tadepalli S, et al., CD301b+ monocyte-derived dendritic cells mediate resistance to radiotherapy. J Exp Med. 2025 Jun 2;222(6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory