Tg(tetO-Plin5)#Peb
Transgene Detail

Summary

• Symbol: Tg(tetO-Plin5)#Peb
• Name: transgene insertion, Perry E Bickel
• MGI ID: MGI:6832825
• Synonyms: TRE-Plin5
• Transgene: Tg(tetO-Plin5)#Peb Location: unknown
• Alliance: Tg(tetO-Plin5)#Peb page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Plin5)#Peb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Plin5 (MGI:1914218)

• Mutation details: The transgene consists of a cDNA encoding mouse Plin5 with an in-frame amino-terminal epitope tag downstream of the tetracycline responsive element (TRE). Plin5 is expressed upon binding of the tetracycline-controlled transactivator (tTA) protein to the promoter. The pound symbol (#) is used because the line is not specified. (J:315837)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:315837 Gallardo-Montejano VI, et al., Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance. Nat Commun. 2021 Jun 3;12(1):3320
• All: 1 reference(s)