Tg(ACTB-EGFP,-NOX1)1Jdla
Transgene Detail
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Symbol: |
Tg(ACTB-EGFP,-NOX1)1Jdla |
Name: |
transgene insertion 1, J Lambeth |
MGI ID: |
MGI:6159583 |
Synonyms: |
Tgnox1 |
Transgene: |
Tg(ACTB-EGFP,-NOX1)1Jdla Location: unknown
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Alliance: |
Tg(ACTB-EGFP,-NOX1)1Jdla page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Tg(ACTB-EGFP,-NOX1)1Jdla expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
NOX1 (27035) |
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conditional: expressed only after removal of floxed EGFP-STOP cassette |
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Mutation details: The transgenic construct is of a CX1 promoter (consisting of a portion of the beta-actin and CMV enhancer sequences), a loxP-flanked EGFP/Stop polyA cassette and the human NOX1 cDNA, This high copy founder line (Tg1) incorporates more than 50 copies of the transgene.
(J:127882)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:127882 Dikalova A, et al., Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation. 2005 Oct 25;112(17):2668-76 |
All: |
1 reference(s) |
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