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Tg(MECP2)1Hzo
Transgene Detail
Summary
Symbol: Tg(MECP2)1Hzo
Name: transgene insertion 1, Huda Y Zoghbi
MGI ID: MGI:3815540
Synonyms: MeCP2Tg1, MECP2-TG1, Tg1
Transgene: Tg(MECP2)1Hzo  Location: unknown  
Alliance: Tg(MECP2)1Hzo page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MECP2)1Hzo expresses 1 gene
 
Mutation detailsA full-length copy of the human gene was injected into FVB fertilized oocytes. Line 1 (2-fold higher levels of protein compared to endogenous Mecp2) was established. (J:94407)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:94407 Collins AL, et al., Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. Hum Mol Genet. 2004 Nov 1;13(21):2679-89
All:  35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory