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insulin dependent diabetes susceptibility 5.2
4 mapping experiments
Experiment Type Details Chromosome Reference
TEXT-Congenic 1 J:88667 Hill NJ, et al., NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans. Diabetes. 2000 Oct;49(10):1744-7
TEXT-Congenic 1 J:143549 Hunter K, et al., Interactions between Idd5.1/Ctla4 and other type 1 diabetes genes. J Immunol. 2007 Dec 15;179(12):8341-9
TEXT-Congenic 1 J:90924 Wicker LS, et al., Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse. J Immunol. 2004 Jul 1;173(1):164-73
TEXT-QTL-Candidate Genes 2 J:107559 Kissler S, et al., In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes. Nat Genet. 2006 Apr;38(4):479-83

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