Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  2
• Reference
  J:28411 Marker PC, et al., Chromosomal localization, embryonic expression, and imprinting tests for Bmp7 on distal mouse chromosome 2. Genomics. 1995 Aug 10;28(3):576-80
• ID
  MGI:46884

Genes

Gene	Assay Type	Description
Ada	reported elsewhere
Svs5	reported elsewhere
Bmp7	Southern analysis	Bmp7 genomic
Pck1	reported elsewhere
Gnas	reported elsewhere

Notes

• Reference
  Authors suggest that Bmp7 is a candiate gene for the flecking (fc) phenotype and for Holt-Oram syndrome, a human genetically heterogeneous disorder that causes heart and skeletal defects.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Ada	Svs5	Bmp7	Pck1	Gnas
69	s	s	s	s	s
47	b	b	b	b	b
7	s	s	b	b	b
1	b	b	s	s	s
1	s	s	s	b	b
0	b	b	b	s	s
0	s	s	s	s	b
1	b	b	b	b	s

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Ada	Svs5	0	126	0.000	0.000
Svs5	Bmp7	8	126	6.349	2.172
Bmp7	Pck1	1	126	0.794	0.790
Pck1	Gnas	1	126	0.794	0.790