Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  17
• Reference
  J:27401 Miyazaki S, et al., The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. Genomics. 1995 Jun 10;27(3):420-4
• ID
  MGI:45948

Genes

Gene	Allele	Assay Type	Description
Map3k4		Southern analysis	pMK174
Eif3s6-ps2		Southern analysis	Int6 cDNA
Pim1		Southern analysis	probe A
Notch4		Southern analysis	probe A
Tnf		Southern analysis	Tnfa probe1
Prph2	Prph2^Rd2	reported elsewhere
Tic1		Southern analysis	pMB20

Notes

• Reference
  Authors use D17Rp17, Cbl1 and Np1 for locus symbols D17Rp17e, Cbl-ps1 and Np respectively. Data in this reference has been deposited in MGD under accession numbers, MGD-CREX-275, 276, 277,278, 279 280, 281, 282 and 283. Due to a confusion in nomenclature, the Chromosome Committtee Reports place Int6 on mouse Chromosome 11. The symbol for this locus is actually Pad2 (see J21517). J27401 correctly maps Int6 to mouse Chromosome 15. Chromosome 17 Pim2 locus defined using a probe pMB20. Probe pMB20 is also associated with Chromosome 17 locus Tic1 as defined by Brewer, M.L. et al., (1989) EMBO J 8:743-747; MGD J9795.

CROSS

• Type
  Backcross, female
• Female Parent
  <n> <n> <n> <n> <n> <n> <n>/<s> <s> <s> <s> <s> <s> <s>
• Strain
  (NFS/N x M. spretus)F1
• Male Parent
  <s> <s> <s> <s> <s> <s> <s>/<s> <s> <s> <s> <s> <s> <s>
• Strain
  M. spretus or C58/J
• Mapping Panel
  Kozak FvC58 + FvSpr
• Allele 1
  n from NFS/N
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Map3k4	Eif3s6-ps2	2	63
Eif3s6-ps2	Pim1	3	53
Pim1	Notch4	6	79
Notch4	Tnf	1	70
Tnf	Prph2	6	70
Prph2	Pim1	1	89

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Map3k4	Eif3s6-ps2	2	65	3.077	2.142
Eif3s6-ps2	Pim1	3	56	5.357	3.009
Pim1	Notch4	6	85	7.059	2.778
Notch4	Tnf	1	71	1.408	1.398
Tnf	Prph2	6	76	7.895	3.093
Prph2	Pim1	1	90	1.111	1.105