Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  1
• Reference
  J:11002 Howard TA, et al., Cd28 and Ctla-4, two related members of the Ig supergene family, are tightly linked on proximal mouse chromosome 1. Immunogenetics. 1991;33(1):74-6
• ID
  MGI:43585

Genes

Gene	Assay Type	Description
Gls	Southern analysis	pGA1
Cd28	Southern analysis	CD28 probe
Ctla4	Southern analysis	F41F4
Inha	Southern analysis

Notes

• Reference
  Authors show data for 113 mice, yet indicate that 114 meiotic events were examined.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <c> <c> <c> <c>/<s> <s> <s> <s>
• Strain
  (C3H/HeJ-Fasl x M. spretus)F1
• Male Parent
  <c> <c> <c> <c>/<c> <c> <c> <c>
• Strain
  C3H/HeJ-Fasl/J
• Mapping Panel
  Seldin
• Allele 1
  c from C3H/HeJ-Fasl/J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Gls	Cd28	Ctla4	Inha
56	c	c	c	c
37	s	s	s	s
1	c	s	s	s
4	s	c	c	c
3	c	c	c	s
12	s	s	s	c

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Gls	Cd28	5	113	4.425	1.935
Cd28	Ctla4	0	113	0.000	0.000
Ctla4	Inha	15	113	13.274	3.192