Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  X
• Reference
  J:14461 Simmler MC, et al., Mapping the murine Xce locus with (CA)n repeats. Mamm Genome. 1993 Sep;4(9):523-30
• ID
  MGI:42636

Genes

Gene	Allele	Assay Type	Description
Eda		visible phenotype
DXPas31		PCR amplified length variant	503A, 503B
Xist		reported elsewhere
Xic		visible phenotype
DXPas29		PCR amplified length variant	230A, 230B
DXPas19		reported elsewhere
DXPas28		PCR amplified length variant	33A, 33B
DXPas27		reported elsewhere
Atp7a	Atp7a^Mo	visible phenotype

Notes

• Experiment
  Using YAC PA-2 anonymous X Chromosome DNA segments, DXPas29 and DXPas28 were located telomeric to Xist, with DXPas29 being 30kb telomeric and DXPas28 lying 20-30kb telomeric. DXPas31 was localized approximately 140kb proximal to Xist. There have been 13 cross-over events detected between Ta and Mo^blo. Typing Xce indicates that 8 of those 13 cross-overs occurred between Xce and Mo^blo (data not shown). DNA from recombinant chromosomes from known parental Xce typings were PCR amplified. Complete linkagebetween DXPas31, Xce, DXPas29 and DXPas28 was observed (data not shown). Authors state since these microsatellite markers and Xce are tightly linked, it suggests a strong concordance between Xce and Xist.