Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  3
• Reference
  J:14460 Birkenmeier EH, et al., The sucrase-isomaltase structural gene (Si-s) and a regulatory gene (Si-r) are closely linked to esterase-26 (Es-26) on mouse chromosome 3. Mamm Genome. 1993 Sep;4(9):531-6
• ID
  MGI:42497

Genes

Gene	Assay Type	Description
Sis	Southern analysis	GC4.5
Si-r	enzyme activity

Notes

• Experiment
  Linkage of Si-s with Si-r on Chromosome 3 was determined by the analysis of 56 F2 male mice derived from an incross between (CBA/CaJ x SJL/J)F1 mice. 12 of the F2 mice expressing low or intermediate sucrase activity may be Si-s and Si-r recombinants or may have resulted from the inclusion of part of the duodenum into the assay. Thus it is possible that Si-r and Si-s did not recombine within the F2 progeny. Overall 77% of the variance in sucrase activity is explained by a genetic factor (Si-r) associated with Si-s.