Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  7
• Reference
  J:13583 Nakatsu Y, et al., A cluster of three GABAA receptor subunit genes is deleted in a neurological mutant of the mouse p locus. Nature. 1993 Jul 29;364(6436):448-50
• ID
  MGI:42430

Genes

Gene	Assay Type	Description
Oca2	Southern analysis	p cDNA, p cDNA1
Gabrg3	Southern analysis	Gabrg-3 cDNA
Gabra5	Southern analysis	Gabra-5 cDNA
Gabrb3	Southern analysis	Gabrb-3 cDNA2, Gabrb-3 cDNA3

Notes

• Experiment
  The following results were obtained from data derived by the hybridization of p, Gabrg3, Gabra5 and Gabrb3 cDNA clones to HindIII digests of DNA from p^cp/p^cp and p^d/p^d mice. p^cp is a deletion in p. p^d mice were used as controls. The 5 prime, but not the 3 prime portion of Gabrb3 was deleted in p^cp. The entire Gabra5 and Gabrg3 genes as well as a 3 prime portion of the p locus are also deleted in p^cp. Exon 1 of the p locus is not deleted in p^cp. These results indicate that the Chromosome7 p^cp deletion extends from intron 1 of the p locus, and includes Gabrg3, Gabra5 and the 5 prime portion of Gabrb3.