Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  X
• Reference
  J:11094 Grant SG, et al., Detailed genetic mapping of the A-raf proto-oncogene on the mouse X chromosome. Oncogene. 1991 Mar;6(3):397-402
• ID
  MGI:41950

Genes

Gene	Assay Type	Description
Cybb	reported elsewhere	Mullins, et al., Genomics 3:187-194, 1988
Otc	reported elsewhere	Mullins, et al., Genomics 3:187-194, 1988
Timp1	reported elsewhere	Gewert, et al., EMBO J 6:651-657, 1987
Araf	Southern analysis	19-1
Syn1	reported elsewhere	Kilimann & DeGennaro, EMBO J 4:1997-2002, 1985
Xlr1	reported elsewhere	Mullins, et al., Genomics 7:19-30, 1990
Hprt1	reported elsewhere	Mullins, et al., Genomics 3:187-194, 1988

Notes

• Experiment
  This cross provides haplotype data for chromosomes recombinant between Otc and Hprt. Additional recombinants between Cybb and Hprt are listed in 2 x 2 table.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6JRos x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b>/Y
• Strain
  C57BL/6JRos
• Allele 1
  b from C57BL/6JRos
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Cybb	Otc	Timp1	Araf	Syn1	Xlr1	Hprt1
88	p	p	p	p	p	p	p
1	s	s	b	b	b	b	b
3	b	b	s	s	s	s	s
1	s	s	s	s	s	b	b
0	b	b	b	b	b	s	s
3	s	s	s	s	s	s	b
4	b	b	b	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Cybb	Otc	3	97
Cybb	Timp1	7	93
Cybb	Araf	7	93
Cybb	Syn1	7	93
Cybb	Xlr1	8	92
Cybb	Hprt1	15	85

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Cybb	Otc	3	200	1.500	0.860
Otc	Timp1	4	100	4.000	1.960
Timp1	Araf	0	100	0.000	0.000
Araf	Syn1	0	100	0.000	0.000
Syn1	Xlr1	1	100	1.000	0.995
Xlr1	Hprt1	7	100	7.000	2.551