Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  2
• Reference
  J:4326 Carlson GA, et al., Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse. Genetics. 1993 Apr;133(4):979-88
• ID
  MGI:41685

Genes

Gene	Allele	Assay Type	Description
Tgm3		visible phenotype
Cenpb		Southern analysis	Cenpb genomic
Adra1d		Southern analysis	738-70
Evi4		Southern analysis	Evi-4 genomic
Prnp		Southern analysis	hamster cDNA
Chgb		Southern analysis
D2Hss1		Southern analysis	D2Hss1 genomic
Pax1	Pax1^un	Southern analysis	pSPT19

Notes

• Reference
  Authors use Spr8 for Gpcr8.
• Experiment
  The 24 recombinants from 451 offspring in this cross were analyzed for the scrapi incubation time gene Prn-i as to delimit its locus within the we-un interval. Here the authors suggest that Prn-i does not lie proximal to Gpcr8 or distal to D2Hss1 and must lie within the Gpcr8-D2Hss1 interval which is approximated at 0.89 cM. Mice congenic between C57BL/6J and I/LnJ were used to confirm this finding.

CROSS

• Type
  Backcross, female
• Female Parent
  <i> <i> <i> <i> <i> <i> <i> <i>/<b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  B6.I/Co x B10.UW/Sn
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  B10.UW/Sn
• Allele 1
  i from B6.I/Co
• Allele 2
  b from B10.UW/Sn

CROSS Data

MC #mice	Tgm3	Cenpb	Adra1d	Evi4	Prnp	Chgb	D2Hss1	Pax1
9	b	b	b	b	b	b	b	i
8	i	i	i	i	i	i	i	b
1	b	b	b	b	b	b	i	i
0	i	i	i	i	i	i	b	b
3	b	b	b	i	i	i	i	i
0	i	i	i	b	b	b	b	b
1	b	b	i	i	i	i	i	i
1	i	i	b	b	b	b	b	b
0	b	i	i	i	i	b	i	i
1	i	b	b	b	b	b	b	b