Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  9
• Reference
  J:3172 Nett MA, et al., Molecular cloning of the murine IL-1 beta converting enzyme cDNA. J Immunol. 1992 Nov 15;149(10):3254-9
• ID
  MGI:40963

Genes

Gene	Assay Type	Description
Mmp12	reported elsewhere	Shapiro, et al., J Biol Chem 267:4664, 1992
Casp1	Southern analysis	Il1bc probe
Ldlr	reported elsewhere	Kingsley, et al., Genetics 123:165, 1989
Epor	reported elsewhere	Shapiro, et al., J Biol Chem 267:4664, 1992
Penk-rs	reported elsewhere	Shapiro, et al., J Biol Chem 267:4664, 1992
Ets1	reported elsewhere	Kingsley, et al., Genetics 123:165, 1989
Thy1	reported elsewhere	Kingsley, et al., Genetics 123:165, 1989

Notes

• Experiment
  Up to 189 mice were typed for individual pairs of loci.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Mmp12	Casp1	Ldlr	Epor	Penk-rs	Ets1	Thy1
47	b	b	b	b	b	b	b
35	s	s	s	s	s	s	s
0	s	b	b	b	b	b	b
0	b	s	s	s	s	s	s
3	s	s	b	b	b	b	b
1	b	b	s	s	s	s	s
1	s	s	s	b	b	b	b
0	b	b	b	s	s	s	s
1	s	s	s	s	b	b	b
1	b	b	b	b	s	s	s
5	s	s	s	s	s	b	b
8	b	b	b	b	b	s	s
5	s	s	s	s	s	s	b
7	b	b	b	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Mmp12	Casp1	0	35
Casp1	Ldlr	1	15
Ldlr	Epor	0	47
Epor	Penk-rs	0	75
Penk-rs	Ets1	4	41
Ets1	Thy1	5	48

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Mmp12	Casp1	0	149	0.000	0.000
Casp1	Ldlr	5	130	3.846	1.687
Ldlr	Epor	1	161	0.621	0.619
Epor	Penk-rs	2	189	1.058	0.744
Penk-rs	Ets1	17	159	10.692	2.451
Ets1	Thy1	17	167	10.180	2.340