Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  12
• Reference
  J:912 Avraham KB, et al., Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3 alpha, HNF-3 beta, HNF-3 gamma, and HNF-4. Genomics. 1992 Jun;13(2):264-8
• ID
  MGI:40870

Genes

Gene	Assay Type	Description
Lamb1	reported elsewhere	Sun, et al., Mol Cell Biol 11:5603-5611, 1991
D12Nyu1	Southern analysis	M13(f)7-97
Foxa1	Southern analysis	HNF-3(alpha)
D12Nyu3	Southern analysis	M13(f)20-1
Sptb	Southern analysis	pM(beta)Sp

Notes

• Reference
  Revised gene symbols Hck, Hnf3a, Hnf3b, Hnf3g, Tcf-4 and Tpi-rs3 (formerly Hck-1, Tcf-3a Tcf-3b, Tcf-3g, Hnf-4 and Tpi-3 respectively).
• Experiment
  Data for 150 mice are presented. Up to 191 mice were analyzed for some pairs of markers producing the following statement of order and distance: centromere - Lamb1-1 - 11.0 +/- 2.3 cM - D12Nyu1 - 2.6 +/- 1.3cM - Tcf-3a - 0.6 +/- 0.6cM - D12Nyu3 - 8.1 +/-2.0cM - Spnb-1.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Lamb1	D12Nyu1	Foxa1	D12Nyu3	Sptb
57	b	b	b	b	b
61	s	s	s	s	s
8	s	b	b	b	b
8	b	s	s	s	s
0	s	s	b	b	b
4	b	b	s	s	s
0	s	s	s	b	b
1	b	b	b	s	s
5	s	s	s	s	b
6	b	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Lamb1	D12Nyu1	5	36
D12Nyu1	Foxa1	0	6
Foxa1	D12Nyu3	0	8
D12Nyu3	Sptb	4	32

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Lamb1	D12Nyu1	21	191	10.995	2.264
D12Nyu1	Foxa1	4	156	2.564	1.266
Foxa1	D12Nyu3	1	158	0.633	0.631
D12Nyu3	Sptb	15	186	8.065	1.997