Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  4
• Reference
  J:11207 Goodwin RG, et al., Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor. Mol Cell Biol. 1991 Jun;11(6):3020-6
• ID
  MGI:39991

Genes

Gene	Assay Type	Description
Lck	reported elsewhere	Ceci, J.D. et al., Genomics 5:699-709, 1989
Fgr	reported elsewhere	Ceci, J.D. et al., Genomics 5:699-709, 1989
Tnfrsf1b	Southern analysis	TNFR-2 cDNA
Nppa	reported elsewhere	Ceci, J.D. et al., Genomics 5:699-709, 1989
Ski	Southern analysis	human Ski-cDNA

Notes

• Reference
  Revised gene symbols: Nppa and Cd4 (formerly Anf and Ly-4 respectively). Numbering for Tnfr genes Tnfr1 (Chromosome 6) and Tnfr2 (Chromosome 4) has been revised to conform to human nomenclature.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Lck	Fgr	Tnfrsf1b	Nppa	Ski
35	b	b	b	b	b
57	s	s	s	s	s
0	b	s	s	s	s
4	s	b	b	b	b
3	b	b	s	s	s
4	s	s	b	b	b
1	b	b	b	b	s
3	s	s	s	s	b

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Lck	Fgr	2	13
Fgr	Tnfrsf1b	0	3
Nppa	Ski	0	9

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Lck	Fgr	6	122	4.918	1.958
Fgr	Tnfrsf1b	7	110	6.364	2.327
Tnfrsf1b	Nppa	0	107	0.000	0.000
Nppa	Ski	4	116	3.448	1.694