Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  2
• Reference
  J:1778 Dolle P, et al., The Hox-4.8 gene is localized at the 5' extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development. Mech Dev. 1991 Dec;36(1-2):3-13
• ID
  MGI:39113

Genes

Gene	Assay Type	Description
Hoxd13	Southern analysis	human HOX-4I probe
Hoxd12

Notes

• Reference
  Revised gene symbols: Hoxd12 and Hoxd13 (formerly Hox-4.7 and Hox-4.8 respectively).
• Experiment
  Mouse genomic cosmid clone cosB carries sequences 5' to the Hoxd12 gene on mouse Chromosome 2. Southern analysis of this cosmid using human HOX-4I probe identified a hybridizing sequence, Hoxd13, 5kb 5' to Hoxd12. Sequencing of a HindIII subclone from cosB confirmed this result. Hoxd8, Hoxd9, Hoxd10, Hoxd11, Hoxd12 and Hoxd13 are spaced regularly 5-10kb apart on a 60kb segment of DNA. No additional Hoxd homeobox genes have been detected 5' of Hoxd13.