Mapping Data

Experiment

• Experiment
  TEXT-QTL-Candidate Genes
• Chromosome
  19
• Reference
  J:88854 Hayashi N, et al., Expression of IKKalpha mRNA in the suprachiasmatic nucleus and circadian rhythms of mice lacking IKKalpha. Brain Res. 2003 Dec 12;993(1-2):217-21
• ID
  MGI:3045032

Genes

Gene	Assay Type
Chuk	reported elsewhere
Lfp1	visible phenotype

Notes

• Experiment
  Search for an Lfp1 candidate gene on distal mouse Chromosome 19 resulted in the consideration of Chuk (45 cM), a helix-loop-helix protein expressed in the hypothalamus. It is thought Chuk may play a role in the regulation of the circadian rhythm. Wheel running activity of heterozygous Chuk mutant mice was compared to wild type. No differences were found in the length of running activity time, angle of entrainment, or amount of running in constant darkness. Therefore, Chuk is not likely a viable candidategene for Lfp1.