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Mapping Data
Experiment
  • Experiment
    TEXT-Physical Mapping
  • Chromosome
    10
  • Reference
    J:86905 Noben-Trauth K, et al., Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss. Nat Genet. 2003 Sep;35(1):21-3
  • ID
    MGI:2683728
Notes
  • Experiment
    Cdh23 was mapped within the congenic interval containing DNA segments D10Mit160 and D10Mit48. Occupying the same congenic region are markers mdfw and ahl. The authors found polymorphisms within this region . The positions of the polymorphisms were orders as D10Ntra57 - D10Ntra42 - D10Ntra39 - Cdh23<10497 del11> - Cdh23 INS7+117A - Cdh23753A - Cdh23685A - D10Ntr46 - D10Ntra48. A significant association of a polymorphism (Cdh23753A) within exon 7 of Cdh23 was suggested to cause the ahl phenotype.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory