Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  10
• Reference
  J:80435 Misawa H, et al., Identification of a Monogenic Locus (jams1) Causing Juvenile Audiogenic Seizures in Mice. J Neurosci. 2002 Dec 1;22(23):10088-93
• ID
  MGI:2447453

Genes

Gene
Bsg
D10Mit140
D10Mit22
D10Mit228
jams1

Notes

• Experiment
  F2 and N2 crosses involving strains 129S1/SvImJ (129) and CAST/Ei and C57Bl/6 mice were informative in mapping the audiogenic seizure susceptibility gene jams1 to mouse Chromosome 10. Genetic analysis of recombinants located the jams1 locus to an 1.6 cM
  area between basigin (Bsg) and marker D10Mit140. Marker D10Mit22 cosegrregated with jams1 in ~1100 meioses. The proximal border of the interval was defined Bsg and D10Mit22, whereas the distal boundary was defined by D10Mit140. jams1 cosegregates with marker D10Mit228 in the intraspecific F2 cross.