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Mapping Data
Experiment
  • Experiment
    TEXT
  • Chromosome
    7
  • Reference
    J:51569 van den Broek FA, et al., Genetic analysis of dystrophic cardiac calcification in DBA/2 mice. Biochem Biophys Res Commun. 1998 Dec 18;253(2):204-8
  • ID
    MGI:2150092
Genes
Notes
  • Experiment
    112 DBA/2Ola x (DBA/2Ola x C57BL/6Ola)F1 backcross animals were typed for 21 microsatellite markers to identify QTLs associated with calcification of soft tissue (myocardium, kidney, and tongue). A major locus was mapped to Dyscalc1 on proximal mouse Chromosome 7 from 18 cM - 39 cM (LOD = 6.5 near D7Mit297). Female animals show higher association to soft tissue calcification and plasma parathyroid hormone levels than male animals at Dyscalc1. The authors suggest that the Hrc gene may be the gene responsible for soft tissue calcification at Dyscalc1.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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