Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  6
• Reference
  J:57711 Depatie C, et al., Assessment of Cmv1 candidates by genetic mapping and in vivo antibody depletion of NK cell subsets. Int Immunol. 1999 Sep;11(9):1541-51
• ID
  MGI:1345817

Genes

Gene	Assay Type	Description
D6Mit61
D6Mit135
D6Mit257
D6Mit289
D6Mit338
Klrb1c
Klrd1	direct sequencing	Cd94-L, Cd94-R
Klrk1	restriction analysis	Nkg2d-R, Nkg2d-L
Klra8	resistance/susceptibility
Klra1	SSLP	D6Ott11-L, D6Ott11-R
Klra3	PCR amplified length variant	Ly49c-L, Ly49c-R
Klra7	SSLP
D6Mit370
D6Mit13
D6Mit111
D6Mit219a
Prh1
Kap
D6Mit374a
D6Mit290
D6Mit220
D6Mit196
D12Mit1000
D6Mit110

Notes

• Experiment
  The authors mapped the markers in the Klra8 region by following the segregation of polymorphisms on a panel of 981 [(A/J x C57BL/6J)F1 x A/J] and 920 [(BALB/c x C57BL/6J)F1 x BALB/c] backcross mice. Analysis of the data reduced the Klra8 candidate regionto a 0.35 cM interval. The locus order and distance for the 7.9 cM segment encompassing Klra8 on mouse Chromosome 6 was: D6Mit216 - 5.1 cM - D6Mit52 - 0.5 cM - D6Mit94 - 0.2 cM - Klrb1c, D6Mit61, D6Mit135, D6Mit257, D6Mit289, D6Mit338 - 0.35 cM - D6H12S2489E, Kldr1 - 0.05 cM - Cmv1, Klra1, Klra3, Klra7, D6Mit370 - 0.3 cM - D6Mit13a, D6Mit111, D6Mit219a, Prh1, Kap - 0.3 cM - D6Mit374a, D6Mit290, D6Mit220, D6Mit196, D6Mit195, D6Mit110. This result excludes Kldr1 and D6H12S2489E as candidates, hereas it localizes Klra1, Klra3 and Klra7 within the Klra8 genetic interval.