Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Xpa
xeroderma pigmentosum, complementation group A
MGI:99135

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	Caption: Microglia activation in the white matter in Ercc2, Ercc6, and Ercc8 mutants (details) Represented Alleles: Ercc2^{tm2(ERCC2)Jhjh}, excision repair cross-complementing rodent repair deficiency, complementation group 2; targeted mutation 2, Jan H J Hoeijmakers Ercc2^tm3Jhjh, excision repair cross-complementing rodent repair deficiency, complementation group 2; targeted mutation 3, Jan H J Hoeijmakers Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Ercc8^tm1Jhjh, excision repaiross-complementing rodent repair deficiency, complementation group 8; targeted mutation 1, Jan H J Hoeijmakers Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(CAG-cre)13Miya/0 mice are severely reduced in size (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(CAG-cre)13Miya, transgene insertion 13, Jun-ichi Miyazaki Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Dilated ventricles and brain atrophy in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Neurodegenerative changes in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 brains (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Neurodegenerative changes in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Pcp2-cre)2Mpin/0 mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Pcp2-cre)2Mpin, transgene insertion 2, Max-Planck-Institute of Neurobiology Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Weight loss in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Gvh/Xpa^tm1Hvs Tg(Camk2a-cre)1Szi/0 mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Brain atrophy after forebrain neuron-specific knockout of Xpa in Ercc6^tm1Gvh/Ercc6^tm1Gvh mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Tg(Camk2a-cre)1Szi, transgene insertion 1, Scott Zeitlin Xpa^tm1Gvh, xeroderma pigmentosum, complementation group A; targeted mutation 1, Gijsbertus T J van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from Jaarsma D, PLoS Genet 2011 Dec;7(12):e1002405, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179808
	Caption: Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs mice display postnatal growth retardation (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from van der Pluijm I, PLoS Biol 2006 Dec 12;5(1):e2, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122013
	Caption: Skeletal and neurological abnormalities in Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs mice (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from van der Pluijm I, PLoS Biol 2006 Dec 12;5(1):e2, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122013
	Caption: Enhanced sensitivity of Ercc6^tm1Gvh/Ercc6^tm1Gvh Xpa^tm1Hvs/Xpa^tm1Hvs retinal photoreceptor cells to ionizing radiation (details) Represented Alleles: Ercc6^tm1Gvh, excision repair cross-complementing rodent repair deficiency, complementation group 6; targeted mutation 1, Gijsbertus van der Horst Xpa^tm1Hvs, xeroderma pigmentosum, complementation group A; targeted mutation 1, Harry van Steeg Copyright: This image is from van der Pluijm I, PLoS Biol 2006 Dec 12;5(1):e2, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:122013

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