Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

App
amyloid beta precursor protein
MGI:88059

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Beta-amyloid plaques in Tg(APPswe,PSEN1dE9)85Dbo/0 mice and neurofibrillary tangles in Mapt^tm1(EGFP)Klt/Mapt^tm1(EGFP)Klt Tg(MAPT)8cPdav/0 mice (details) Represented Alleles: Mapt^tm1(EGFP)Klt, microtubule-associated protein tau; targeted mutation 1, Kerry Lee Tucker Tg(APPswe,PSEN1dE9)85Dbo, transgene insertion 85, David R Borchelt Tg(MAPT)8cPdav, transgene insertion 8c, Peter Davies Copyright: This image is from Phillips M, PLoS One 2011;6(5):e19567, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:172426
	Caption: Amyloid beta deposits in App^tm3.1Zhe/App^tm3.1Zhe Psen1^tm1Mpm/Psen1^tm1Mpm mice (details) Represented Alleles: App^tm3.1Zhe, amyloid beta precursor protein; targeted mutation 3.1, Hui Zheng Psen1^tm1Mpm, presenilin 1; targeted mutation 1, Mark P Mattson Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379
	Caption: Neuromuscular synapse defects in App^tm3.1Zhe/App^tm3.1Zhe Aplp2^tm1Dbo/Aplp2^tm1Dbo mice (details) Represented Alleles: Aplp2^tm1Dbo, amyloid beta precursor-like protein 2; targeted mutation 1, David R Borchelt App^tm3.1Zhe, amyloid beta precursor protein; targeted mutation 3.1, Hui Zheng Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23