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Phenotype Images associated with this Gene
Symbol
Name
ID
b2b2187Clo
Mutant line 2187
MGI:5491168


33 phenotype image(s) for b2b2187Clo alleles
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Caption: Mutant 2187-004-NC has a hypoplastic aorta and pulmonary stenosis as well as DORV and biventricular hypertrophy that was confirmed by EFIC imaging (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2187-004-NC shows DORV, subaortic VSD, and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-004-NC exhibits a short snout, micrognathia, and abnormal flexure of the hindlimb (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-004-NC has a cleft palate (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-004-NC shows an unfused sternum (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-004-NC exhibits a hypoplastic thymus (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-004-1 (E16.5) has hydrocephalus, build up of blood in the brain, and hydrops when it was collected (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-004-1 (E16.5) exhibits pulmonary stenosis and double outlet right ventricle (DORV) that confirmed EFIC histology (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory