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Phenotype Images associated with this Gene
Symbol
Name
ID 		b2b2187Clo
Mutant line 2187
MGI:5491168


33 phenotype image(s) for b2b2187Clo alleles
Showing image(s) 11 to 20 		Show   figures per page Start Previous Next Last
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Caption: Serial 2D EFIC image stack in the coronal plane of 2187-004-1 (E16.5) shows double outlet right ventricle (DORV), subaortic VSD, small LV, atrioventricular valve dysplasia, semilunar valve dysplasia, bicuspid aortic valve, and a spongy right ventricle
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant fetus 2187-004-1 (E16.5) in the transverse view shows aliasing with increased blood flow through inflow tracts, suggesting atrioventricular valve stenosis (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant fetus 2187-004-1 (E16.5) in the sagittal view shows aliasing with increased velocity of blood flow in pulmonary artery (PA), suggesting pulmonary stenosis (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Spectral Doppler imaging of mutant fetus 2187-00401 (E16.5) in the sagittal view detects increased velocity of blood flow in pulmonary artery (PA), suggesting pulmonary stenosis, which is consistent with the findings of color flow imaging (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-006-2 (E15.5) has hindlimbs with abnormal flexure and hydrops (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2187-006-2 (E15.5) shows overriding aorta, pmVSD, mild hypoplastic aorta, and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2187-006-4 (E15.5) shows overriding aorta, perimembranous VSD (pmVSD), muscular VSD (mVSD), and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2187-004-NA presents with an unfused sternum (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory