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Symbol Name ID |
Traf7
TNF receptor-associated factor 7 MGI:3042141 |
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Caption: Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (-/-) embryos show developmental delay. Almost all E10.5 embryos have abnormal head shape and cardiac tissue, some with enlarged hearts and pericardial edema, abnormal branchial arch development, and abnormal blood deposition. Yolk sacs appear pale.
(details)
Represented Alleles:
Traf7em1(IMPC)Tcp,
TNF receptor-associated factor 7; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (-/-) placentas exhibit multiple labyrinth zone defects. Thickness of the labyrinth layer is reduced and chorioallantoic branching is nearly absent.
(details)
Represented Alleles:
Traf7em1(IMPC)Tcp,
TNF receptor-associated factor 7; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: E9.5 AlleleSymbol(MGI:6388361|0)/Traf7em1(IMPC)Tcp (Traf7-/-) embryos display appropriate germ layer formation. Embryos are mainly normal, displaying normal heart and liver development.
(details)
Represented Alleles:
Traf7em1(IMPC)Tcp,
TNF receptor-associated factor 7; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: AlleleSymbol(MGI:6388361|0)/Traf7em1(IMPC)Tcp (-/-) embryos display appropriate germ layer formation at E10.5, however embryos are delayed and a reduction in cellular density, most easily seen in head sections, is seen.
(details)
Represented Alleles:
Traf7em1(IMPC)Tcp,
TNF receptor-associated factor 7; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 01/06/2026 MGI 6.24 |
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