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Symbol Name ID |
Mmp21
matrix metallopeptidase 21 MGI:2664387 |
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Caption: Mutant 2458-002-LA exhibits heterotaxy with levocardia, right lung isomerism (3R/3L), dextrogastria, and interrupted aortic arch which is confirmed by EFIC imaging
(details)
Represented Alleles:
Mmp21b2b2458Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 2458 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Dextrocardia with anterior aorta, right pulmonary isomerism with bilateral 3 lung lobes, and mirror symmetric liver situs.
(details)
Represented Alleles:
Mmp21b2b873Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 873 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Mmp21b2b2458Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 2458 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Heterotaxy indicated by dextrocardia, transposition of the great artery (TGA), right pulmonary isomerism, and mirror symmetric abdominal organ situs.
(details)
Represented Alleles:
Mmp21b2b873Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 873 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack in the coronal plane of 2458-002-LA shows TGA {A,D,D}, unbalanced AVSD, common atrium, hypoplastic RV, interrupted aortic arch (type B), and right lung isomerism
Click thumbnail to play movie. (details) Represented Alleles:
Mmp21b2b2458Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 2458 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: 2D serial EFIC images in the coronal view reveals dextrocardia {S(A), D, D}, and tricuspid atresia type IIc (transposition)
Click thumbnail to play movie. (details) Represented Alleles:
Mmp21b2b873Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 873 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2458-002-LA shows immotile cilia
Click thumbnail to play movie. (details) Represented Alleles:
Mmp21b2b2458Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 2458 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: 2D serial EFIC images in the transverse view reveals LV inlet and mitral valve
Click thumbnail to play movie. (details) Represented Alleles:
Mmp21b2b873Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 873 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2458-002-LA exhibits heterotaxy with right lung isomerism (3R/3L) and hypoplastic LV
(details)
Represented Alleles:
Mmp21b2b2458Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 2458 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: 3D EFIC volume rendering reveals left-sided IVC
Click thumbnail to play movie. (details) Represented Alleles:
Mmp21b2b873Clo,
matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 873 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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