Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Adam17
a disintegrin and metallopeptidase domain 17
MGI:1096335

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	Caption: Failure of eyelid closure, enlarged aortic, pulmonic, and tricuspid heart valves, and enlarged zone of hypertrophic chondrocytes in growth plates of Rhbdf1^{tm1b(EUCOMM)Wtsi}/Rhbdf1^{tm1b(EUCOMM)Wtsi} Rhbdf2^tm1Mak/Rhbdf2^tm1Mak (iR1/2-/-) and Adam17^tm1.1Bbl/Adam17^tm1.1Bbl mice. (details) Represented Alleles: Adam17^tm1.1Bbl, a disintegrin and metallopeptidase domain 17; targeted mutation 1.1, Carl P Blobel Rhbdf1^{tm1b(EUCOMM)Wtsi}, rhomboid 5 homolog 1; targeted mutation 1b, Wellcome Trust Sanger Institute Rhbdf2^tm1Mak, rhomboid 5 homolog 2; targeted mutation 1, Tak Mak Copyright: This image is from Li X, Proc Natl Acad Sci U S A 2015 May 12;112(19):6080-5. Copyright 2015 National Academy of Sciences, U.S.A. J:221411
	Caption: Thickened pulmonic valve leaflets and growth plate abnormality inRhbdf1^{tm1b(EUCOMM)Wtsi}/Rhbdf1^{tm1b(EUCOMM)Wtsi} Rhbdf2^tm1Mak/Rhbdf2^tm1Mak (iR1/2-/-) and Adam17^tm1.1Bbl/Adam17^tm1.1Bbl mice (details) Represented Alleles: Adam17^tm1.1Bbl, a disintegrin and metallopeptidase domain 17; targeted mutation 1.1, Carl P Blobel Rhbdf1^{tm1b(EUCOMM)Wtsi}, rhomboid 5 homolog 1; targeted mutation 1b, Wellcome Trust Sanger Institute Rhbdf2^tm1Mak, rhomboid 5 homolog 2; targeted mutation 1, Tak Mak Copyright: This image is from Li X, Proc Natl Acad Sci U S A 2015 May 12;112(19):6080-5. Copyright 2015 National Academy of Sciences, U.S.A. J:221411
	Caption: Adam17^tm1Imx/Adam17^tm1Imx embryos develop internal hemorrhage (details) Represented Alleles: Adam17^tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217
	Caption: Vascular defects and hemorrhage in Adam17^tm1Imx/Adam17^tm1Imx embryos (details) Represented Alleles: Adam17^tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217
	Caption: Vascualr abnormalities in Adam17^tm1Imx/Adam17^tm1Imx embryos (details) Represented Alleles: Adam17^tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217
	Caption: Abnormal fusion of branches in Adam17^tm1Imx/Adam17^tm1Imx cranial vessels (details) Represented Alleles: Adam17^tm1Imx, a disintegrin and metallopeptidase domain 17; targeted mutation 1, Immunex Copyright: This image is from Canault M, PLoS One 2010;5(10):e13433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:166217

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