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Phenotype Images associated with this Allele
Nomenclature
Symbol: Rhbdf1tm1b(EUCOMM)Wtsi
Name: rhomboid 5 homolog 1; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5792831
Synonyms: iR1-, iRhom1-, Rhbdf1v2
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Failure of eyelid closure, enlarged aortic, pulmonic, and tricuspid heart valves, and enlarged zone of hypertrophic chondrocytes in growth plates of Rhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi Rhbdf2tm1Mak/Rhbdf2tm1Mak (iR1/2-/-) and Adam17tm1.1Bbl/Adam17tm1.1Bbl mice.Rhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi
Rhbdf2tm1Mak/Rhbdf2tm1Mak
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * FVB/N
Adam17tm1.1Bbl/Adam17tm1.1Bblinvolves: 129P2/OlaHsd * C57BL/6 * FVB/N
Thickened pulmonic valve leaflets and growth plate abnormality inRhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi Rhbdf2tm1Mak/Rhbdf2tm1Mak (iR1/2-/-) and Adam17tm1.1Bbl/Adam17tm1.1Bbl miceRhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi
Rhbdf2tm1Mak/Rhbdf2tm1Mak
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * FVB/N
Adam17tm1.1Bbl/Adam17tm1.1Bblinvolves: 129P2/OlaHsd * C57BL/6 * FVB/N

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory