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Phenotype Images associated with this Allele
Nomenclature
Symbol: Lmnatm1Rben
Name: lamin A; targeted mutation 1, Ricardo Benavente
MGI ID: MGI:5695312
Synonyms: Lamin C2-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Small testes and absence of post-meiotic cells in the Lmnatm1Rben/Lmnatm1Rben testesLmnatm1Rben/Lmnatm1Rbeninvolves: 129S1/Sv * 129X1/SvJ
Defective synapsis of the homologous chromosomes in Lmnatm1Rben/Lmnatm1Rben meiocytesLmnatm1Rben/Lmnatm1Rbeninvolves: 129S1/Sv * 129X1/SvJ
Bouquet release is significantly delayed in Lmnatm1Rben/Lmnatm1Rben spermatocytesLmnatm1Rben/Lmnatm1Rbeninvolves: 129S1/Sv * 129X1/SvJ
Alterations of meiotic DNA double-strand break repair and inefficient homologous recombination in Lmnatm1Rben/Lmnatm1Rben miceLmnatm1Rben/Lmnatm1Rbeninvolves: 129S1/Sv * 129X1/SvJ
Complete absence of mature sperm and increased cell death in testis of Lmnatm1Rben/Lmnatm1Rben miceLmnatm1Rben/Lmnatm1Rbeninvolves: 129S1/Sv * 129X1/SvJ

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory