Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Dmd^tm1.1Know
Name:	dystrophin, muscular dystrophy; targeted mutation 1.1, Kirk Knowlton
MGI ID:	MGI:5569634
Synonyms:	Dys^KI

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Decreased susceptibility to coxsackievirus B3 viral infection of the heart in Dmd^tm1.1Know/Dmd^tm1.1Know mice	Dmd^tm1.1Know/Dmd^tm1.1Know	involves: C3H
	Inhibition of dilated cardiomyopathy in Dmd^tm1.1Know/Dmd^tm1.1Know Tg(Myh6-2A)#Know/0 A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/0 mice	Dmd^tm1.1Know/Dmd^tm1.1Know A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ Tg(Myh6-2A)#Know/0	involves: BALB/c * C3H * C57BL/6 * FVB/N
	Decrease in fibrosis in Dmd^tm1.1Know/Dmd^tm1.1Know Tg(Myh6-2A)#Know/0 A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/0 hearts	Dmd^tm1.1Know/Dmd^tm1.1Know A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ Tg(Myh6-2A)#Know/0	involves: BALB/c * C3H * C57BL/6 * FVB/N

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