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Phenotype Images associated with this Allele
Nomenclature
Symbol: Bub1btm1.1Hsl
Name: BUB1B, mitotic checkpoint serine/threonine kinase; targeted mutation 1.1, Hyunsook Lee
MGI ID: MGI:5543300
Synonyms: BubR1K243R
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Spontaneous tumorigenesis in Bub1btm1.1Hsl/Bub1b+ miceBub1btm1.1Hsl/Bub1b+involves: 129 * C57BL/6
Splenomegaly with B cell lymphoma in Bub1btm1.1Hsl/Bub1b+ miceBub1btm1.1Hsl/Bub1b+involves: 129 * C57BL/6
B cell hyperproliferation consisting of large, often fragmented, nuclei with irregular shapes in Bub1btm1.1Hsl/Bub1b+ lymph nodesBub1btm1.1Hsl/Bub1b+involves: 129 * C57BL/6
B cell hyperproliferation consisting of large, often fragmented, nuclei with irregular shapes in Bub1btm1.1Hsl/Bub1b+ lymph nodesBub1btm1.1Hsl/Bub1b+involves: 129 * C57BL/6
Megakaryocytic leukemia in the Bub1btm1.1Hsl/Bub1b+ miceBub1btm1.1Hsl/Bub1b+involves: 129 * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory